ABC GEZONDHEID - Artikels
14 februari 2024
Vitamine C, therapeutisch bij lichte en zware infecties
| 14/02/2024 |
| 14/02/2024 |
Veruit de meest bekende vitamine, antioxidant, maar tevens betrokken bij een groot aantal lichaamsprocessen: bescherming lichaamscellen, ondersteuning weerstand, enz... Vitamine C is wateroplosbaar en moet dus elke dag weer aangevuld worden. Minder bekend is dat vitamine C een dubbele werking heeft:
- In lage (dagelijkse) dosis werkt het als antioxidant en recycleert het andere antioxidanten zoals vitamine E. Dagelijkse aanvoer gebeurt best via de voeding of natuurlijke supplementen met bioflavonoïden, de natuurlijke gezellen van vitamine C in voedsel.
- Maar in hoge stootdosissen wordt vitamine C een oxidant, en antimicrobieel. Dit kan gebruikt worden bij een infectie. Het lichaam verbruikt dan zeer veel vitamine C en wordt snel deficiënt. Dit kan je dus zelf gebruiken bij verkoudheid of griep (tot 10 gram/dag)
In de geneeskunde worden zelfs hogere stootdosissen (10, 20 tot 50 gram,…) intraveneus toegediend bij ernstige infecties zoals longontsteking, ARDS, Covid-19, sepsis,…
Door de wetenschappelijke bewijzen wordt de effectiviteit van vitamine C-therapie eindelijk stilaan erkend.
Weerstand verhogen bij kinderen
De immuniteit verhogende eigenschappen van vitamine C
Meer lezen:
Oxidatieve stress
Bang voor virussen? Versterk je weerstand!
Citroensap versterkt de werking van groene thee
Vitamines, pro- en halfvitamines… allemaal belangrijk!
Bronnen:
Abioye AI et al. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Global Health 2020 https://gh.bmj.com/content/6/1/e003176
Hung KC et al. Impact of intravenous vitamin C as a monotherapy on mortality risk in critically ill patients: A meta-analysis of randomized controlled trials with trial sequential analysis. Front Nutr. 2023 Mar 24; 10:1094757.
Mahmoodpoor A et al. Effect of Vitamin C on mortality of critically ill patients with severe pneumonia in intensive care unit: a preliminary study. BMC Infectious diseases 2021; 21:616.
Hoang BX et al. Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection. J Glob Antimicrob Resist. 2020; 23: 256–262.
Cheng RZ et al. Early Large Dose Intravenous Vitamin C is the Treatment of Choice for 2019-nCov Pneumonia. OMNS 2020. http://orthomolecular.org/resources/omns/v16n11.shtml
Fang L et al. Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial. BMJ Open 2020. https://bmjopen.bmj.com/content/10/7/e039519
Fowler AA et al. Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome. World J Crit Care Med. 2017;6:85–90.
Gonzalez MJ, Berdiel MJ, Duconge J. High dose vitamin C and influenza: A case report. J Orthomol Med. June, 2018, 33(3). https://isom.ca/article/high-dose-vitamin-c-influenza-case-report.
Carr AC, Maginni S. Vitamin C and Immune Function. Nutrients 2017; 9: 1211-1236.
Bharara A et al. Intravenous vitamin C administered as adjunctive therapy for recurrent acute respiratory distress syndrome. Case Rep Crit Care 2016:8560871.
Kim Y et al. Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection. Immune Network. 2013;13(2):70-74.
Zarubaeva VV et al. Protective activity of ascorbic acid at influenza infection. Russian J Infection and Immunity 2017; 7, (4): 319–326.
Wilson JX. Evaluation of vitamin C for adjuvant sepsis therapy. Antioxid Redox Signal. 2013 Dec 10;19(17):2129-40.
Syed AA, Knowlson S, Sculthorpe R. Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. J Transl Med. 2014; 12:32. 2013;19:2129–2140.
Abioye AI et al. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Global Health 2020 https://gh.bmj.com/content/6/1/e003176
Hung KC et al. Impact of intravenous vitamin C as a monotherapy on mortality risk in critically ill patients: A meta-analysis of randomized controlled trials with trial sequential analysis. Front Nutr. 2023 Mar 24; 10:1094757.
Mahmoodpoor A et al. Effect of Vitamin C on mortality of critically ill patients with severe pneumonia in intensive care unit: a preliminary study. BMC Infectious diseases 2021; 21:616.
Hoang BX et al. Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection. J Glob Antimicrob Resist. 2020; 23: 256–262.
Cheng RZ et al. Early Large Dose Intravenous Vitamin C is the Treatment of Choice for 2019-nCov Pneumonia. OMNS 2020. http://orthomolecular.org/resources/omns/v16n11.shtml
Fang L et al. Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial. BMJ Open 2020. https://bmjopen.bmj.com/content/10/7/e039519
Fowler AA et al. Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome. World J Crit Care Med. 2017;6:85–90.
Gonzalez MJ, Berdiel MJ, Duconge J. High dose vitamin C and influenza: A case report. J Orthomol Med. June, 2018, 33(3). https://isom.ca/article/high-dose-vitamin-c-influenza-case-report.
Carr AC, Maginni S. Vitamin C and Immune Function. Nutrients 2017; 9: 1211-1236.
Bharara A et al. Intravenous vitamin C administered as adjunctive therapy for recurrent acute respiratory distress syndrome. Case Rep Crit Care 2016:8560871.
Kim Y et al. Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection. Immune Network. 2013;13(2):70-74.
Zarubaeva VV et al. Protective activity of ascorbic acid at influenza infection. Russian J Infection and Immunity 2017; 7, (4): 319–326.
Wilson JX. Evaluation of vitamin C for adjuvant sepsis therapy. Antioxid Redox Signal. 2013 Dec 10;19(17):2129-40.
Syed AA, Knowlson S, Sculthorpe R. Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. J Transl Med. 2014; 12:32. 2013;19:2129–2140.
De gegevens op deze site zijn zuiver van informatieve aard en pas bruikbaar na een diagnose door een geneeskundige, therapeut of voedingsdeskundige. Raadpleeg eerst een deskundige en sla nooit professioneel advies in de wind.
